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Sci-Tech

Health Canada- Covid Vaccination Is Safe But…

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COVID Vaccination Is ‘Safe’ but Remains Clinically Untested for Pregnant Women: Health Canada

COVID Vaccination Is ‘Safe’ but Remains Clinically Untested for Pregnant Women: Health Canada
A sign is displayed in front of Health Canada headquarters in Ottawa on Jan. 3, 2014. (The Canadian Press/Sean Kilpatrick)

Nearly four years after the launch of the massive COVID-19 vaccination campaign, which included mandates and passports, the safety of the products for pregnant women remains mostly untested clinically.

Health Canada answered a series of questions from Tory MP Colin Carrie in April about the issue.

“What specific research data supported the claims that … this product may be safely administered at any stage of pregnancy?” asked Mr. Carrie in an Inquiry of Ministry.

“Please note that the vaccine manufacturers did not seek an indication for use in pregnant and lactating women and the Product Monographs included statements about the uncertainty regarding safety and efficacy in pregnancy and lactation,” answered Health Canada, which is responsible for authorizing vaccines in Canada.

The product monographs for the widely administered COVID-19 shots from Pfizer-BioNTech and Moderna, which describe the properties, claims, indications, and conditions of use for the drug, state the unavailability of data regarding use during pregnancy.

“No data are available yet regarding the use of COMIRNATY Omicron XBB.1.5 during pregnancy,” said Pfizer-BioNTech’s monographs, both for its updated Omicron injection and its original one.

Health Canada Asked Pfizer for DNA Fragments Size in COVID Shots, Linked to ‘Probability’ of Genomic ‘Integration’

“The safety and efficacy of SPIKEVAX XBB.1.5 in pregnant women have not yet been established,” similarly say Moderna’s monographs for its updated Omicron shots and its legacy product.

Pfizer-BioNTech’s initial clinical trial for pregnant women, announced publicly in February 2021, encountered recruitment problems.

A Pfizer Canada representative told a member of the National Advisory Committee for Immunization (NACI) in April 2022 that the trial had been stopped due to slow enrolment, according to internal emails seen by The Epoch Times.

Jelena Vojicic, vaccines medical lead at Pfizer Canada, also said “it became unreasonable/inappropriate to randomize pregnant women to placebo given the amount of observational evidence that the vaccine is safe and effective, coupled with increasing number of technical committees supporting immunization of pregnant women.”

Despite hurdles, Pfizer-BionTech submitted results for a small clinical trial with 348 participants in July 2023, according to the U.S. government website ClinicalTrials.gov.

Moderna’s observational pregnancy outcome study was terminated in the fall of 2023 due to low enrolment, with ClinicalTrials.gov noting 20 enrolled participants.

Neither Pfizer nor Moderna responded to a request for comment.

While confirming there is little to no clinical trial data, Health Canada said vaccination for pregnant women was recommended based on evidence of safety and effectiveness growing from “real-world use.”

“Analysis of the data show that mRNA COVID-19 vaccines are safe for people who are pregnant or breastfeeding.”

Dr. Bernard Massie, a virologist and former National Research Council acting director general of the Human Health Therapeutic Research Center, raised doubts about the reliability of data obtained outside clinical trials, calling them “very incomplete and often biased.”

“We won’t find what we’re not looking for,” noting that real-world passive surveillance of side effects can be underrepresented by a factor of 10 and up to a 100 for lax systems.

‘Off-Label’

While Health Canada authorizes vaccines, the regulator said that NACI is responsible for formulating recommendations for public use.

“This means that NACI may provide recommendations that are broader or narrower than the conditions of use approved by Health Canada, often referred to as ‘off-label’ recommendations,” said spokesperson Anna Maddison, adding such a practice by NACI is ”not uncommon.” Ms. Maddison also noted the COVID-19 vaccines are not contraindicated in pregnant or lactating women.

At the beginning of the vaccine rollout, NACI said in December 2020 that pregnant or breastfeeding mothers “should not” in most circumstances be offered the vaccine “until further evidence is available.”

The recommendation was changed in January 2021 to “may be offered” following a risk assessment.

By May 2021, NACI had updated its recommendation for pregnant women that they “should be offered” COVID-19 mRNA shots.

To back its recommendation, NACI cited a U.S. government study of 35,000 pregnant women using data from December 2020 to February 2021.

“Preliminary findings did not show obvious safety signals among pregnant persons who received mRNA Covid-19 vaccines,” said the study. It noted, however, that “more longitudinal follow-up, including follow-up of large numbers of women vaccinated earlier in pregnancy, is necessary to inform maternal, pregnancy, and infant outcomes.”

Dr. Massie questioned whether the study by government scientists was interested in finding issues with vaccination and pregnancy given that the government was promoting mass vaccination.

After the results of the study were published on April 21, 2021 in the New England Journal of Medicine, other government advisory bodies recommended COVID-19 vaccination in pregnant women.

Quebec’s government announced vaccination would be offered to pregnant women on April 27 of that year, citing a recommendation from its immunization committee which “analyzed the evolution of scientific data and recommendations in different countries.”

B.C.’s government recommendation came on May 4, 2021. “All Health Canada-approved vaccines are safe and effective, and I encourage everyone to register and receive their vaccine as soon as they are eligible. Today, this includes people who are pregnant,” said Dr. Bonnie Henry, B.C.’s provincial health officer.

‘Not’ Advertising

Dr. Philip Oldfield, who has more than three decades of experience specializing in the bioanalysis of protein/nucleic acid therapeutics and regulatory affairs, raised questions about the product monographs for vaccines saying effects on pregnancy were not tested while government bodies encourage pregnant women to be vaccinated. 

He also points to passive surveillance data on vaccine adverse events collected in the United States showing over 2,000 miscarriages following COVID-19 vaccination. While this data doesn’t prove causality, it is considered largely underreported.

Dr. Oldfield said Health Canada encouraging pregnant women to get vaccinated for COVID-19 could contradict “both the law with respect to false and misleading advertisements of a drug, and contradicts the safety data found on both the Moderna and Pfizer monographs.”

The Epoch Times asked Health Canada if it is allowed by law to make recommendations about the use of products for certain populations for which the products’ monographs do not indicate safety information. The Foods and Drugs Act states that “No person shall label, package, treat, process, sell or advertise any drug in a manner that is false, misleading or deceptive or is likely to create an erroneous impression regarding its character, value, quantity, composition, merit or safety.”

Health Canada spokesperson Anna Madison responded that “public health messages from a government authority that promote vaccination would not qualify as advertising of a health product.”

Despite different bodies’ recommendations for pregnant woman, NACI noted in a summer 2022 report that “uptake of COVID-19 vaccine has been lower among pregnant people compared to non-pregnant people in Canada.”

“Preliminary unpublished evidence in Ontario indicates that primary series vaccine coverage among pregnant people (71 percent) was 16 percentage points lower than in the general female population of reproductive age in Ontario by the end of 2021.”

Animal Studies

Outside of emerging real-word evidence, regulators and advisory bodies have also cited studies conducted on animals to determine the safety for pregnant women and their babies.

“Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryo/fetal development, parturition, or post-natal development, and human randomized clinical trials were not submitted for regulatory evaluation,” said Health Canada in responding to MP Carrie.

The NACI also cited a study conducted on rats with Pfizer’s mRNA vaccine to back its recommendation, saying no issues were encountered.

A Moderna nonclinical overview submitted to the U.S. government and obtained by legal advocacy group Judicial Watch through a lawsuit indicates the presence of “statistically significant increases” in rat offsprings with “wavy ribs and 1 or more rib nodules.” 

“There were no other indicators of mRNA-1273-related developmental toxicity observed, including delayed ossification; therefore, these common skeletal variations were not considered adverse,” concluded the manufacturer.

Both Dr. Oldfield and Dr. Massie said the animal studies conducted are not proper to assess risk in humans. “Using an inappropriate species in the Developmental and Reproductive Toxicity (DART) studies would never pick up the toxic effects due to the spike protein,” said Dr. Oldfield. “The animal studies were performed using an inappropriate species (rat) which unlike humans, their ACE receptors does not bind to the vaccine generated spike protein.”

Breastfeeding

MP Carrie also raised the issue of breastfeeding in his request for information to the government, asking what specific research data there is to say that “modRNA vaccine, and consequently the spike protein, do not excrete into breast milk.”

Health Canada responded that the product monographs for authorized COVID-19 vaccines “include a statement that it is unknown whether the COVID-19 vaccine is excreted in human milk.”

“A risk to newborns/infants cannot be excluded,” it adds.

Studies have found mRNA from COVID shots does end up in breast milk, with a recent one published in the medical journal Lancet in September.

In response to previous questions, Health Canada told Mr. Carrie last year that “mRNA-encoded spike protein is only expressed transiently and at the injection site and the liver, then declines over time.”

Authors of the study published in the Lancet noted their “findings demonstrate that the COVID-19 vaccine mRNA is not confined to the injection site but spreads systemically and is packaged into [breast extracellular vesicles].”

The scientists said that since only “trace quantities” are present and a “clear translational activity is absent, we believe breastfeeding post-vaccination is safe, especially 48 h after vaccination.” They specified that since the minimum mRNA dose to elicit an immune reaction in young infants is unknown, breastfeeding mothers should consult with a health-care provider to discuss risks and benefits in the first two days after vaccination. For the Silo, Noé Chartier/Epoch Times.

Noé Chartier
Sci-Tech

Lyme Disease In Canada And USA Has Epidemic Potential- New Microbes Discovered

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Spring means fresh flowers and sunny days, but it also brings seasonal health issues as the weather gets warmer: from Rosacea to Lyme disease.

Most likely, you or someone you know has been affected by Lyme disease, the most common tick-borne illness in North America with more than 300,000 cases diagnosed each year. In a timely new book, Conquering Lyme Disease(Columbia University Press), Columbia University Medical Center physicians Brian A. Fallon and Jennifer Sotsky reveal that despite the challenges to find a cure for this complex, debilitating disease, precision medicine and biotechnology are accelerating the discovery of new tools with which doctors will be able to diagnose it and treat patients.

“Through rapid genetic sequencing, scientists can identify many different strains of Borrelia burgdorferi as well as new tick-borne microbial infections, such as Borrelia miyamotoi, Borrelia mayonii, and the Heartland virus.”  — Brian Fallon 

Could groundbreaking technologies that rapidly increase our understanding and open up new pathways mean a cure for Lyme disease one day soon? The Global Search for Education is pleased to welcome Dr. Brian Fallon to find out how tech is tackling the ticks.

“Modern technology using Next-Generation Sequencing (NGS) allows one to discover with great rapidity all microbes that may be present within a sample of fluid.” — Brian Fallon

Brian, how has technology improved the research process for tick borne diseases?

Consider the difference in price of genome sequencing between 20 years ago and today. In 2003, it had taken the Human Genome Project about 4 years and costs estimated between $500 million to 1 billion…by 2006 the cost for sequencing a single human genome had dropped to 14 million……today a whole human genome can be sequenced within days for less than $1,000.   This is a tremendous advance.

Why is genome sequencing so important?  Let’s look at human tick-borne diseases.  When two different people are infected with Borrelia burgdorferi (the microbe that causes Lyme disease), one will resolve the disease quickly after a course of antibiotics while the other may develop a chronic relapsing remitting illness.  Why?  Because one person might have gotten a more persistent strain, while the other received  a less invasive strain that stays localized to the skin.  Additionally, the genetic differences in the human determines how the immune system responds to the invading microbe. Understanding the genetics of the infection and of the human host allows scientists to unravel the mysteries of tick-borne illnesses.

Through rapid genetic sequencing, scientists can identify many different strains of Borrelia burgdorferi as well as new tick-borne microbial infections, such as Borrelia miyamotoi, Borrelia mayonii, and the Heartland virus.  When the genome of a microbe is sequenced, it provides a starting point for the study of pathogenesis, vaccine development, and treatment.  Discovery of these new microbes inside ticks has been enormously helpful.  A patient who has had typical symptoms of Lyme disease after a tick bite but has tested negative on the blood tests for Lyme disease might puzzle clinicians. They may criticize the insensitivity of the Lyme disease tests.  However, when this same patient is tested for the newly discovered tick-borne infection, Borrelia miyamotoi, the diagnosis is then clear. Yes, the patient had a Lyme-like illness, but it wasn’t Lyme disease: it was Borrelia Miyamotoi disease.

Modern technology using Next-Generation Sequencing (NGS) allows one to discover with great rapidity all microbes that may be present within a sample of fluid.   This  “discovery based” approach using “unbiased next generation sequencing” enabled a 14 year old boy to be rescued from a fatal infection within 48 hours (Wilson et al, NEJM, 2014). This boy had endured 3 hospitalizations over 4 months, had over 100 diagnostic tests, spent 44 days in an ICU for encephalitis of unknown etiology, had a brain biopsy, and had to be put into a medically induced coma to prevent damage from his ongoing seizures.

Eventually Dr. Charles Chiu at U.C.S.F. employed NGS analysis of more than 8 million sequences with a bioinformatics pipeline (SURPI) for the detection of all known pathogens. The cause of the boy’s meningoencephalitis was revealed as Leptospira santarosai. He had likely acquired it in Puerto Rico, as it is not present in the continental United States.  He received the appropriate antibiotics and was discharged 2 weeks later to rehab.  This same approach is especially useful for uncommon infections as they might not be suspected; for example, rare tick-borne viruses such as Powassan Virus or Heartland Virus can be rapidly  detected using this discovery approach.

DNA Double Helix
DNA Double Helix

How has big data impacted the way advocacy groups support research?

A patient-generated source of Big Data is LymeDisease.org.  This California based organization developed a survey called “My Lyme Data” that patients could fill out on the web about their clinical history and lab tests and treatments.  In a short period of time, they had data on 10,000 patients whom they track over time.  With this information, they provide a more comprehensive clinical view of the bulk of patients who are diagnosed with persistent symptoms despite treatment for Lyme Disease (aka Chronic Lyme Disease).

“In geographic areas where medical professionals are scarce, AI technologies will play an increasing role in improving patient care by allowing differential diagnoses to be generated and treatment options suggested through AI-based systems accessed through the internet.”  — Brian Fallon

Jobs in all professions are being automated. Do you believe AI technologies will only assist doctors or will they replace physicians in some tasks? What does this mean for doctors, nurses, and the future of medicine?

Borrelia transmission via Tick
Borrelia

While AI technologies will go a long way to assist health care providers to provide better care, its application to medical care is still just beginning.   One can anticipate, however,  that in geographic areas where medical professionals are scarce, AI technologies will play an increasing role in improving patient care by allowing differential diagnoses to be generated and treatment options suggested through AI-based systems accessed through the internet.

The general public has more access to information than ever before about Lyme disease from websites, medical organizations, articles and social media. Everyone can be their own “expert” or even their own “doctor.”  Can you speak about the pros and cons of online health data in the era of fake news?

This obviously is a huge area of concern. Individuals used to turn to their physician or to the medical information books, such as the Merck Manual. Now, they turn to the web.

In a recent survey of patients who used the web to obtain health information (Doherty-Torstrick 2016), we learned that more than half of the 730 patients reported they experienced increased distress as a result of checking the web.  We also learned from this survey that individuals who did not have a health education were more likely to spend more time on the web and were thus prone to develop more anxiety than those who were better educated from a health perspective.   While some of the information they find may be accurate, other information may be well-intentioned but ill-informed, misleading, and even harmful.

“Researchers can rapidly screen thousands of drugs to determine which agents have the strongest ability to kill Borrelia spirochetes.  This is possible because of the development of high throughput assays, which have proven more effective than the standard agents in eradicating both the stationary phase Borrelia and its more drug-tolerant persister-forms.” — Brian Fallon

Tick distribution Canada

Look into the future.  What are the technologies you are most excited about in terms of helping to find cures for Lyme disease and improve patients quality of life?

Researchers can rapidly screen thousands of drugs to determine which agents have the strongest ability to kill Borrelia spirochetes (Feng 2014).  This is possible because of the development of high throughput assays, which have identified new antibiotics that have proven more effective than the standard agents (doxycycline, amoxicillin) in eradicating both the stationary phase Borrelia and its more drug-tolerant persister-forms.  While it cannot be assumed that what is true in the lab setting will translate to efficacy in humans, biotechnology advances have enabled the identification of new therapeutic agents, offering  much hope for a wider array of treatment options for patients in the future.

Another major advance is “big data” conducted by biomedical information engineers trained in biostatistics and computer science.  Internet search engine queries are being monitored to predict outbreaks of infectious disease.  Unanticipated side effects of drugs and their interactions can be detected through analyzing millions of digital medical records from patients who have taken a particular drug.  One can examine whether patients given an antibiotic did better when treated for longer or shorter periods, or whether patients with a pre-existing autoimmune disease are more likely to develop complications from a new onset Tick-borne infection than those without a history of autoimmune problems.

Tick
2005 James Gathany; William Nicholson
The blacklegged ticks, I. pacificus, (depicted here), and I. scapularis, are known vectors for the zoonotic spirochetal bacteria Borrelia burgdorferi, which is the pathogenic bacteria responsible for causing Lyme disease. The ticks, inoculated with the bacterium when they bite infected mice, squirrels and other small animals, subsequently pass the pathogens to their human victims when they obtain a blood meal.B. burgdorferi bacteria can infect several parts of the body, producing different symptoms at different times. Not all patients with Lyme disease will have all symptoms, and many of the symptoms can occur with other diseases as well. If you believe you may have Lyme disease, it is important that you consult your health care provider for proper diagnosis.
The first sign of infection is usually a circular rash called “erythema migrans”, or EM. This rash occurs in approximately 70-80% of infected persons and begins at the site of a tick bite after a delay of 3-30 days. A distinctive feature of the rash is that it gradually expands over a period of several days, reaching up to 12 inches (30 cm) across. The center of the rash may clear as it enlarges, resulting in a bull’s-eye appearance. It may be warm but is not usually painful. Some patients develop additional EM lesions in other areas of the body after several days. Patients also experience symptoms of fatigue, chills, fever, headache, and muscle and joint aches, and swollen lymph nodes. In some cases, these may be the only symptoms of infection.

Our Lyme and Tick-borne Diseases Research Center, located at the Columbia University Irving Medical Center (CUIMC) in New York City, is right next door to an international data resource.  CUIMC is the coordinating center of a public health information initiative which includes medical records from approximately 400 million people drawn from eighty health-care organizations from around the world.  This represents a unique opportunity  to ask questions, generate hypotheses and get answers about Tick-borne diseases.  When discovery is optimized, medical care is enhanced.

For the Silo, David Wine/CM RubinWorld. 

Brian Fallon, MD, MPH is the Director of the Lyme and Tick-Borne Diseases Research Center at the Columbia University Irving Medical Center and the author with Jennifer Sotsky of Conquering Lyme Disease: Science Bridges the Great Divide, published in 2018 by Columbia University Press.

Culture

Africa without vaccines while Canada doses are wasted

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Canada just moved from having enough doses to vaccinate every Canadian, into a surplus position.

This also means that Canada reached a new very problematic milestone. Doses are going bad in Canada, while desperate people, including frontline health workers in Africa, are still struggling to get access to vaccines.

None of us are safe until all of us are safe. We know this pandemic isn’t truly over until it is over everywhere. Canada MUST share more of our excess doses now. Canada MUST resist the urge to offer 3rd dose “boosters” to healthy Canadians (some of whom are getting them in order to vacation in the Caribbean) while nurses in Senegal are still unprotected.

We have more than enough vaccines, others don’t.

Africa is facing a COVID-19 crisis, cases are surging and the continent is heading towards a global catastrophe. Over the last month deaths from COVID in Africa have increased 80%. Only roughly 3% of Africans have received the first shot, and the continent is not on track to vaccinate 10% of its population by the end of the year. The WHO’s Bruce Aylward said this should be “a scar on all of our consciences.”

What can Canada do?

Meanwhile in Canada, Prime Minister Trudeau announced on July 27th that with 66 million doses received, we have enough to fully vaccinate every eligible Canadian. We have now reached a point where the supply of vaccine exceeds demand, and already Astra Zeneca doses have been thrown away and Moderna vaccines are sitting in freezers nearing their expiry dates.

Canada is the country that has ordered the most vaccines per person: counting optional purchases, enough to vaccinate each Canadian 5 times. Unless the excess doses are shared right now, we could end-up throwing away millions of doses while most of the rest of the world remains unvaccinated. This is a scandal that we cannot let happen.

Vaccines being discarded is not a theoretical concern. In addition to the 300,000 doses from Johnson and Johnson that were discarded due to a manufacturing issue, thousands of Astra Zeneca doses have already been wasted in Canada because they could not be used before their expiry dates. With this vaccine barely been used in anymore, there may be thousands more sitting in freezers or the garbage, and provinces are coy about how many they may be throwing away.  The same is starting to happen with Moderna, with pharmacists unable to put some of the doses they have in arms.

Figure 1: A tale of two pandemics
While Canada is in a very good position, some African countries are seeing an increase in cases with a very small share of their population vaccinated.


Canada has so far committed to share 30.7 million doses with COVAX, the global vaccine distribution mechanism, including a recent pledge to donate the remainder of our Astra Zeneca orders. But there has been no confirmation of when these donated vaccines might reach countries in need.

In addition, new analysis by the ONE Campaign based on data from analytics firm AirFinity shows that at the current rate, Canada will end-up with between 16 and 42 million more vaccines piling up in freezers or thrown away by Christmas, while the pandemic continues raging on in Africa and the developing world.

We not only have a moral obligation to share doses, it is in our own best interest to stop the global spread and emergence of new variants. Until then, more preventable deaths will occur and Canada’s own recovery will be threatened by a shaky global economy. According to the IMF, failing to help the developing world defeat Covid-19 could cost the global economy US$4.5 trillion.

The time to donate more doses is now. Lives depend on it.

Africa is experiencing an increasingly urgent COVID crisis and needs at least 200 million vaccine doses by the end of September to slow the spread and prevent more needless deaths. Canada should immediately transfer all incoming vaccine orders to COVAX, beyond ensuring that there are enough for every Canadians to be fully vaccinated. This should mean at least 12 million more doses shared before the end of September, and in total 16-42 million vaccines donated before the end of the year if we want to end the pandemic and avoid unimaginable waste.

Vaccines being discarded is not a theoretical concern. In addition to the 300,000 doses from Johnson and Johnson that were discarded due to a manufacturing issue, thousands of Astra Zeneca doses have already been wasted in Canada because they could not be used before their expiry dates. With this vaccine barely been used in anymore, there may be thousands more sitting in freezers or the garbage, and provinces are coy about how many they may be throwing away.  The same is starting to happen with Moderna, with pharmacists unable to put some of the doses they have in arms.

It may be tempting for the Government to keep vaccines stockpiled just in case boosters may be needed. But the evidence so far on the need for boosters is far from conclusive, and many experts have warned that it would be counterproductive to start giving third doses to healthy people in rich countries while at-risk populations have not yet had their first shot in developing countries. Stockpiling a product with a short shelf life will inevitably lead to a lot of waste. In any case, Canada has already ordered up to 60 million more doses of Pfizer a year for the next 3 years in case boosters are needed.

The excess doses we have coming in the next 5 months must urgently be shared with countries in need to stem the pandemic globally. Variants spreading around the world pose a threat to Canadians. The longer we wait to vaccinate the world, the more variants we will see and the longer this vicious cycle will continue. The time to donating more doses is now. Lives depend on it.

Up to 42 million doses could go unused in Canada by Christmas

By December 2021, Canada will have received at least 92 million doses of the four vaccines currently approved by Health Canada (Moderna, Pfizer, Astra Zeneca and Johnson & Johnson). If Medicago and Novavax post positive Phase 3 results and are also approved, total supply could increase to 117 million doses. [1]

To fully vaccinate every Canadian, including children under 12 should vaccines be approved for them, 76 million doses will be required in total. These are highly optimistic projections of actual demand, since it is unlikely that 100% of the population will want to be vaccinated.

This means that between 16 and 42 million excess vaccines risk being stockpiled or wasted in Canada by the end of the year. The higher scenario means our excess vaccines would be enough to fully vaccinate everyone in a country like Burkina Faso this year. Right now, 0.01% of people are fully vaccinated in Burkina Faso. For the Silo, Justin McAuley.

Figure 2: A growing stockpile
Even accounting for the already-announced donations, Canada will have millions of excess vaccines

[1] This excludes the 30 million doses already donated to Covax.

Politics

How Covid Affects Ontario Legislature

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The past week has been a whirlwind of activity in Ontario politics.    Some have asked about my absence from the Legislature for the vote on May 31.    

With the advent of COVID-19, all political parties decided to divide the sitting members of the Legislature into two groups with equal representation from all parties. 

Separate groups in the Legislature are an attempt to diminish the spread of COVID-19.  

The Legislature is divided into two groups or cohorts in case COVID-19 swept through the sitting members, which could result in all members being in quarantine and the Legislature grinding to a halt. Instead, with two groups, only part of the Legislature would end up in quarantine and the other half could take over.   

My group was not designated to be in the Legislature May 31. For this reason, I was not present in the House. All parties agreed to not have remote voting in the Ontario Legislature. I am presently working from home, including serving virtually on Standing Committees.    

The motion passed on Monday relates to the ability to extend and amend existing orders under the Reopening Ontario Act. Orders made under the Act’s authority have always been, and will continue to be, required to be extended in 30-day increments by Cabinet. All orders may also be amended by Cabinet at any time to loosen or tighten restrictions as necessary. These Orders have been the mechanism that we use to implement the COVID-19 response since last July, including the colour-coded framework, the shutdown, and now the roadmap to reopening.   

Please note that the declaration of emergency and Stay-at-Home orders have expired as a result of key indicators for COVID-19 trending in the right direction and significant progress being made in vaccinations.   

However, because of the new, fast-growing Indian B.1.617.2 and to allow for higher vaccination rates, our government made the difficult decision to continue with remote learning for all elementary and secondary students across the province for the remainder of this school year. This will allow the province to continue its focus on accelerating COVID-19 vaccinations to support a safe summer and return to in-person learning in September for the 2021-22 school year.   

The health and safety of Ontario students, staff, educators and families remains a top priority.  

On a personal note, my wife Cari and I both contracted COVID-19 and have completely recovered.  Cari is home from Joseph Brant Hospital and is doing very well after a week-and-a-half there, including one week in Intensive Care. We have ended our self-isolation, although we continue to follow public health guidelines.     

We can’t begin to express our appreciation for all the messages of support and concern – thank you everyone!!    

My positive test for the N501Y mutation of the UK B.1.1.7 variant was a result of picking up the virus just prior to my vaccination.

The changing face of the pandemic: New COVID-19 variants spark concern

We must also be vigilant as the new B.1.617.2 variant, which was first identified in India and entered the province through Canada’s international borders, grew in Ontario by 600 per cent from May 12 to May 19.  

The threat of new variants reinforces my belief that we all must continue to be cautious because of this highly transmissible disease.    For the Silo, Toby Barrett MPP for Haldimand-Norfolk.   

Culture

UK PM Johnson: You May Need Vaccination Proof To Enter Pubs

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51%

Only days after it was announced that 51% of British adults have received at least one doses of their COVID vaccine, Prime Minister Boris Johnson has said that people may need to present a vaccination certificate in order to go to the pub. One month ago, Johnson had said that this would not be the case.

One Year Later

When the UK first entered lockdown one year ago, Johnson recognized he was “taking away the ancient, inalienable right of free-born people of the United Kingdom to go to the pub” but now he is suggesting limits on how many of them will be given back that right.

British political analyst and commentator Jonathan Sacerdoti says the UK’s vaccination program has been impressive, beating the rest of Europe by far. “This has been for three main reasons,” he explains. “Firstly, the UK implemented skillful procurement of vaccines, which enabled the country to ensure a plentiful if varying supply level of the newly developed vaccines. Having finally broken free of the European Union after years of Brexit back-and-forth, the UK was able to make its own decisions just in time, and signed early and favorable contracts with vaccine manufacturers.”

AstraZeneca

“Secondly, the UK also invested in developing its own vaccine, the Oxford AstraZeneca vaccine. This has offered a far cheaper alternative to the Pfizer BioNtech vaccine which the UK is also using, and is far easier to transport. It does not require the deep refrigeration that some other vaccines do, and it can therefore also be administered in pharmacists and smaller medical practices, or even in old age homes, rather than only in mass vaccination centers. Despite some concerns over possible blood clots as a side effect, the vaccine is widely accepted to be safe and effective. It has enabled the UK to make progress with vaccinating its population quickly, and promises to help vaccinate poorer countries around the world.”

Extended Dosage Gap

“Thirdly, the UK made the controversial decision to extend the gap between the two vaccine doses each person needs, from 21 days to 12 weeks. This was not backed up but he vaccine makers’ research, but was based on wider knowledge of immunology and how other vaccines have been developed. At the time it was seen as highly controversial and even risky. But ongoing testing for antibodies has shown a continued, strong immune response even with the prolonged gap. This single decision has enabled the country to effectively provide a high level of protection to double the number of people in the same time. As long as vaccine supply and availability continue uninterrupted, the second doses will be given within 12 weeks and the population will continue to benefit both individually and as a whole.”

EU Lags

Meanwhile, the European Union is lagging far behind in its rate of vaccination, causing a rift between the bloc and its recent ex-member state the UK. Threats of banning or controlling exports of vaccines manufactured in the EU to countries which are far ahead in their programs has caused a diplomatic war of words. The UK determined to have its commercial contracts fulfilled regardless of the EU’s weak performance in acquiring and administering vaccines. The EU is desperate to claw back more vaccines for use in its own countries, despite slow progress in administering them.

Jonathan Sacerdoti is a British broadcaster and social commentator, widely featured on British and international television and media. He provides commentary for a wide range of TV stations including regular appearances on the BBC (including on their international show Dateline London) and the UK’s Sky News. He also appears on Channel 4 News, Al Jazeera English, NDTV in India, France 24, i24News Cheddar News and others. He has been published by the Daily Telegraph, The Spectator, the New Statesman and Jewish Chronicle. He is also a well-known campaigner on racism issues.