Tag Archives: melanoma

Must Do Sun Safety Tips For Wintertime

Preventing, Minimizing and Repairing Damage from Exposure 

I hope you didn’t pack away the sunblock with your swimsuit and other summer accessories because believe it or not, the winter’s sun is just as dangerous as summer’s, says Adam J. Scheiner, M.D, an eyelid and facial cosmetic surgeon who’s been featured on The Dr. Oz Show, The Howard Stern Show and The Doctors. In fact, in certain wintry conditions the sun is actually more dangerous. Read on….

“The snow reflects the glare of the sun – and the damaging UV rays,” he says. “People who like skiing and snowboarding in the mountains are getting 4 to 5 percent more UV damage for every 1,000 feet they ascend above sea level.”

The winter sun sits much lower than the summer sun and one reason why it’s harmful rays are a threat.

And then there are all those holiday cruises and escapes to warm-weather climates where beaches are packed year-round. “It’s not OK to lie baking in the sun for hours, even if it’s just one week out of the winter, while you’re enjoying your tropical getaway.” Dr. Scheiner says.

No matter how comfortable or cool the temperature feels, don’t be fooled.

Adam Scheiner
Adam Scheiner

“Just a few years ago, in 2020, the United States surgeon general predicted 9,000 people would die from melanoma. Those deaths were all preventable,” Dr. Scheiner says. 

“And if skin cancer doesn’t scare you, think with your vanity. Sun exposure is the number one cause of wrinkles, discoloration, age spots and festoons, among other disfiguring problems.”

Dr. Scheiner shares tips for preventing, minimizing and repairing sun damage:

•  Prevention: You’re not just exposed when you’re skiing, hiking, or taking a beach vacation.

“Anytime you go outside, you’re exposing yourself to damaging UVB and UVA rays, and the result is cumulative. A little bit here and a little there adds up,” Scheiner says.

Simply driving a car can result in serious sun damage. A study published in the Journal of the American Academy of Dermatology found more skin cancers on the left side of patients’ faces – the side exposed while driving – then the right. Scheiner says he’s seen truckers and others who spend years on the road with severe wrinkling on the left side of the face.

“Always wear sunscreen, which protects against UVA and UVB rays. I recommend a Broad Spectrum Sunscreen with an SPF (sun protection factor) of at least 30, preferably higher,” he says. “You can also protect yourself from UVA rays, which cause deeper damage, by applying UV-protective film to your car windows. Also, wear clothes with a UPF (ultraviolet protection factor) rating of at least 30.”

•  Minimizing: Good nutrition and topical products can help minimize signs of damage, such as wrinkles and age spots, Dr. Scheiner says.

Eat foods rich in antioxidants — carrots and other yellow and orange fruits and vegetables; spinach and other green leafy vegetables; tomatoes; blueberries; peas and beans; fatty fish, and nuts. An American Society for Clinical Nutrition study found that women ages 40 to 75 who consumed more vitamin C, an antioxidant, had fewer wrinkles.

Use exfoliate creams to remove dead skin cells. Prescription creams including Avita, Avage, Renova and Retin-A have been shown to reduce wrinkles and age spots caused by sun exposure.

•  Repairing:  Lasers can resurface facial skin by stripping away the outermost layers. Some “non-ablative” lasers also stimulate collagen formation, which helps smooth wrinkles.

“I use RESET® Laser Skin Resurfacing, which reverses the damage and removes many pre-cancers and even active skin cancers,” Scheiner says. “RESET uses an advanced Dual Pulsed Erbium Laser, and my proprietary healing protocol. “

The RESET® treatment Dr. Scheiner has vaporizes the old skin and causes the collagen in the underlying layers to tighten.

Reset Skin Laser Resurfacing

The No. 1 best thing you can do for your skin starting today is to start making application of a broad spectrum, UVB/UVA sunscreen part of your daily routine. Apply it to all areas of the skin that can be directly exposed to the sun, the best scenario is preventing sun damage in the first place. For the Silo, Jarrod Barker. 

Using Laser Technology to Detect Cancer Cells

We’ve come a long way since hearing Dr. Evil of Austin Powers’ movie fame describe “a sophisticated heat beam, which we call ‘a laser’ ” to take over the world, or sitting in awe watching Jedi knights in Star Wars blast through enemies using lightsabers.   

Now in real life, lasers are being used to detect cancers cells. 

Cancer tumors have the ability to break off of their primary site and spread from their primary organ to other sites of the body via the bloodstream and lymphatic system.  The spreading of cancer, known as “metastasis”, is the leading cause of cancer-related death.  Although, there are currently blood tests designed to detect cancer cells in the blood, known as circulating tumor cells, these test many times cannot pick up minimal cancer cells released early on.   If these current tests return as positive, this frequently means that there is a high level of cancerous cells in the blood that have spread to other organs.

However, the diagnosis and treatment of these cancer cells in the blood may soon change.

  In a recent study published in Science Translation Medicine, researchers have devised a laser that can detect these malignant cells and ‘zap’ them from outside of the body.  The current standard methods of detection have limited sensitivity for picking up minimal cells at early stages of the disease, therefore possibly missing an opportunity to eliminate them at a treatable juncture.   A team led by biomedical engineer Vladimir Zharov, director of nanomedicine at the University of Arkansas for Medical Sciences, has developed a method in hopes of changing that modality.

In studies with melanoma, they have coupled a laser with an ultrasound detector to create a ‘Cytophone,’ a device that identifies cells acoustically. 

To break it down, a laser is first shined on the surface of a person’s skin, penetrating right into some of the near-surface blood vessels.  The passing melanoma cells will then ‘heat up’ because of their darker pigment and create a small ‘acoustic wave’ that then gets picked up by the ultrasound detector.   Melanoma cells absorb more of the energy from the laser because of their dark pigment, allowing them to heat up quickly and expand.

This devised method can pick up a single circulating tumor cell per liter of blood, which makes this up to approximately 1,000 times more sensitive than other available methods of detection that typically examine only about 7- 8 milliliters of a sample of blood.  Additionally, the cytophone was able to detect small clots of blood that could potentially grow and lead to another set of harmful consequences. 

They have tested this on 28 patients with melanoma and 19 healthy volunteers. 

Researchers were able to discover that within as little as 10 seconds and as long as 1 hour, the cytophone was able to detect circulating tumor cells in 27 of the 28 patients.  It also did not return any false positives on the healthy volunteers.  Moreover, it was found that when the energy level of the laser was turned up (still to a safe intensity) that the amount of circulating tumor cells came down over the hour, without causing any side effects. 

Although the mechanism will likely not destroy all of the patient’s cancer cells, it can help in several different ways.  Initially, it can be used in high-risk individuals as a screening tool to detect cancer cells in the blood.  Similar to mammograms in breast cancer, it can be added to skin checks in patients that are at high risk for melanoma.  While undergoing treatment, it could potentially be used to monitor the effects of that particular treatment, in addition to or separate from imaging and other blood tests, to determine if the circulating cancer cells in the blood are decreasing.   Following the completion of treatment, it can be used to monitor for relapse of disease. 

Even though this has been tested recently in melanoma, and the dark pigment of melanin plays a role in its detection, Zharov and his colleagues are currently working to develop methods of ‘tagging’ other cancer cells with small nanoparticles to be able to ‘heat up’ and be distinguished from the normal cells.  This study holds promise but it now needs to be expanded to in a larger population including patients with a higher content of melanin.  For the Silo, Jerry McGlothlin.

Movies aside, the future holds promise in the new hope of using lasers to fight off the evil invasions of metastasis.

About Joshua Mansour, MD…

Dr. Joshua Mansour is a board-certified hematologist/oncologist working and in the field of hematopoietic stem cell transplantation and cellular immunotherapy in Stanford, California. In June 2019 he was a recipient of the ‘40 Under 40 in Cancer’ award. Abstracts, manuscripts, and commentaries by Dr. Mansour have been published in more than 100 esteemed journals and media outlets including Canada Free Press, Today’s Practitioner, Physician’s News, and KevinMD. He has given countless presentations at conferences and other institutions, and he has helped design and implement clinical studies to evaluate current treatment plans, collaborated on grant proposals and multi-institutional retrospective studies that have been published. Joshua Mansour. M.D. has been featured on Fox Television.