Tag Archives: cancer

Must Do Sun Safety Tips For Wintertime

December 4, 2024 The Silo Leave a comment

Preventing, Minimizing and Repairing Damage from Exposure

I hope you didn’t pack away the sunblock with your swimsuit and other summer accessories because believe it or not, the winter’s sun is just as dangerous as summer’s, says Adam J. Scheiner, M.D, an eyelid and facial cosmetic surgeon who’s been featured on The Dr. Oz Show, The Howard Stern Show and The Doctors. In fact, in certain wintry conditions the sun is actually more dangerous. Read on….

“The snow reflects the glare of the sun – and the damaging UV rays,” he says. “People who like skiing and snowboarding in the mountains are getting 4 to 5 percent more UV damage for every 1,000 feet they ascend above sea level.”

The winter sun sits much lower than the summer sun and one reason why it’s harmful rays are a threat.

And then there are all those holiday cruises and escapes to warm-weather climates where beaches are packed year-round. “It’s not OK to lie baking in the sun for hours, even if it’s just one week out of the winter, while you’re enjoying your tropical getaway.” Dr. Scheiner says.

No matter how comfortable or cool the temperature feels, don’t be fooled.

“Just a few years ago, in 2020, the United States surgeon general predicted 9,000 people would die from melanoma. Those deaths were all preventable,” Dr. Scheiner says.

“And if skin cancer doesn’t scare you, think with your vanity. Sun exposure is the number one cause of wrinkles, discoloration, age spots and festoons, among other disfiguring problems.”

Dr. Scheiner shares tips for preventing, minimizing and repairing sun damage:

• Prevention: You’re not just exposed when you’re skiing, hiking, or taking a beach vacation.

“Anytime you go outside, you’re exposing yourself to damaging UVB and UVA rays, and the result is cumulative. A little bit here and a little there adds up,” Scheiner says.

Simply driving a car can result in serious sun damage. A study published in the Journal of the American Academy of Dermatology found more skin cancers on the left side of patients’ faces – the side exposed while driving – then the right. Scheiner says he’s seen truckers and others who spend years on the road with severe wrinkling on the left side of the face.

“Always wear sunscreen, which protects against UVA and UVB rays. I recommend a Broad Spectrum Sunscreen with an SPF (sun protection factor) of at least 30, preferably higher,” he says. “You can also protect yourself from UVA rays, which cause deeper damage, by applying UV-protective film to your car windows. Also, wear clothes with a UPF (ultraviolet protection factor) rating of at least 30.”

• Minimizing: Good nutrition and topical products can help minimize signs of damage, such as wrinkles and age spots, Dr. Scheiner says.

Eat foods rich in antioxidants — carrots and other yellow and orange fruits and vegetables; spinach and other green leafy vegetables; tomatoes; blueberries; peas and beans; fatty fish, and nuts. An American Society for Clinical Nutrition study found that women ages 40 to 75 who consumed more vitamin C, an antioxidant, had fewer wrinkles.

Use exfoliate creams to remove dead skin cells. Prescription creams including Avita, Avage, Renova and Retin-A have been shown to reduce wrinkles and age spots caused by sun exposure.

• Repairing: Lasers can resurface facial skin by stripping away the outermost layers. Some “non-ablative” lasers also stimulate collagen formation, which helps smooth wrinkles.

“I use RESET® Laser Skin Resurfacing, which reverses the damage and removes many pre-cancers and even active skin cancers,” Scheiner says. “RESET uses an advanced Dual Pulsed Erbium Laser, and my proprietary healing protocol. “

The RESET® treatment Dr. Scheiner has vaporizes the old skin and causes the collagen in the underlying layers to tighten.

The No. 1 best thing you can do for your skin starting today is to start making application of a broad spectrum, UVB/UVA sunscreen part of your daily routine. Apply it to all areas of the skin that can be directly exposed to the sun, the best scenario is preventing sun damage in the first place. For the Silo, Jarrod Barker.

Earth

Why Canadians Must Get More Sunlight

August 23, 2024 The Silo 4 Comments

TORONTO – Following restrictive sun exposure advice in countries with low solar intensity like Canada might in fact be harmful to your health, says the co-author of a new study on sunlight and vitamin D.

The published study Sunlight and Vitamin D: Necessary for Public Health by Carole Baggerly and several academic researchers, examines how organizations such as World Health Organization’s International Agency for Research on Cancer and the U.S. Surgeon General call for sun avoidance, but ignore the fact that cutting out sunshine will reduce vitamin D, an essential vitamin for bone health, and create probable harm for the general population.

“Humans have adapted to sun exposure over many thousands of years and derive numerous physiological benefits from UV exposure, in addition to vitamin D,” said Baggerly, executive director of Grassroots Health and breast cancer survivor.

“These benefits are in addition to those derived from vitamin D alone and cannot be replaced by vitamin D supplements and therefore sun avoidance being recommended by the US Surgeon General, the Canadian Cancer Society, the Canadian Dermatology Association and others, is unnecessarily putting Canadians at risk.”

From mercola.com -studies suggest we need more sunlight than currently recommended dosages

Vitamin D is an essential vitamin that enables calcium absorption and is critical for good bone health. Low levels are linked to bone conditions such as rickets in children and osteomalacia and osteoporosis in adults.

In Canada, vitamin D from sunlight can only be synthesized in the skin during the spring, summer and fall months, around midday, from 10 a.m. – 2 p.m., when the UV index is above three and your shadow is shorter than your height.

Statistics Canada reports that 12 million Canadians, or 35% of the population, have insufficient vitamin D levels, including 10% who are severely deficient, which sets them up for higher disease risk.

According to Dr. Reinhold Vieth, Scientific Advisor for the Canadian Vitamin D Consensus and professor at the University of Toronto in the Department of Laboratory Medicine and Pathobiology, “If organizations warn people to stay out of the sun, then they should also let people know that they will not be producing vitamin D. Both the risks and benefits of UV exposure need to be addressed in the best interest of health. Unfortunately, the message Canadians keep hearing lately is that there is no benefit to being in the sun. The paper by Baggerly et al presents a clear case that good overall health does correlate with spending time in the sun.”

A group comprised of the Multiple Sclerosis Society of Canada, Vitamin D Society and Pure North S’Energy Foundation, have endorsed a draft Canadian Vitamin D Consensus which recommends that Canadians enjoying the sun safely, while taking care not to burn, can acquire the benefits of vitamin D without unduly raising the risk of skin cancer.

Vitamin D deficiency is an indication of sunlight deficiency.

“People today work less outdoors and spend less time outdoors than at any previous time in history, which is why vitamin D deficiency is rising globally. In addition, when people are outside, many use sunscreens, which can significantly prevent the production of vitamin D in the skin,” said Dr. Vieth. “With increasing amounts of evidence suggesting that vitamin D may protect against cancer, heart disease, diabetes, multiple sclerosis and other chronic diseases, it’s more important than ever to examine this issue more closely.”

“We urge public health entities to re-evaluate their current sun exposure policies and recommend UV exposure levels that promote a balanced, moderate approach that are both beneficial and safe,” said Baggerly.

About the Vitamin D Society:

The Vitamin D Society is a Canadian non-profit group organized to increase awareness of the many health conditions strongly linked to vitamin D deficiency; encourage people to be proactive in protecting their health and have their vitamin D levels tested annually; and help fund valuable vitamin D research. The Vitamin D Society recommends people achieve and maintain optimal 25(OH)D blood levels between 100 – 150 nmol/L (Can) or 40-60 ng/ml (USA).

Sci-Tech

Researchers Discover New Mechanism Linking Diet and Cancer Risk

July 20, 2024 The Silo Leave a comment

MGO, a glucose metabolite, can temporarily destroy the BRCA2 protein, reducing its levels in cells and inhibiting its tumor-preventing ability.

Via friends at epochtimes. You may have heard that sugar feeds cancer cells, and evidence supports that. However, the missing link in this narrative has been a thorough understanding of just “how” sugar feeds cancer—until now. A recent study published in Cell in April uncovers a new mechanism linking uncontrolled blood sugar and poor diet with cancer risk.

The research, performed at the National University of Singapore’s Cancer Science Institute of Singapore, and led by professor Ashok Venkitaraman and Li Ren Kong, a senior research fellow at the University of Singapore, found a chemical released when the body breaks down sugar also suppresses a gene expression that prevents the formation of tumors.

This discovery provides valuable insights into how one’s dietary habits can impact their risk of developing cancer and forges a clear path to understanding how to reverse that risk with food choices.

Methylglyoxal–A Temporary Off Switch

It was previously believed that cancer-preventing genes must be permanently deactivated before malignant tumors can form. However, this recent discovery suggests that a chemical, methylglyoxal (MGO), released whenever the body breaks down glucose, can temporarily switch off cancer-protecting mechanisms.

Mr. Kong, first author of the study, stated in a recent email: “It has been shown that diabetic and obese individuals have a higher risk of cancer, posing as a significant societal risk. Yet, the exact cause remains debatable.

“Our study now unearthed a clue that may explain the connection between cancer risk and diet, as well as common diseases like diabetes, which arise from poor diets.

“We found that an endogenously synthesized metabolite can cause faults in our DNA that are early warning signs of cancer development, by inhibiting a cancer-preventing gene (known as the BRCA2).”

BRCA2 is a gene that repairs DNA and helps make a protein that suppresses tumor growth and cancer cell proliferation. A BRCA2 gene mutation is associated primarily with a higher risk of developing breast and ovarian cancers, as well as other cancers. Those with a faulty copy of the BRCA2 gene are particularly susceptible to DNA damage from MGO.

However, the study showed that those without a predisposition to cancer also face an increased risk of developing the disease from elevated MGO levels. The study found that chronically elevated levels of blood sugar can result in a compounded increase in cancer risk.

“This study showcases the impact of methylglyoxal in inhibiting the function of tumour suppressor, such as BRCA2, suggesting that repeated episodes of poor diet or uncontrolled diabetes can ‘add up’ over time to increase cancer risk,” Mr. Kong wrote.

The Methylglyoxal and Cancer Relationship

MGO is a metabolite of glucose—a byproduct made when our cells break down sugar, mainly glucose and fructose, to create energy. MGO is capable of temporarily destroying the BRCA2 protein, leading to lower levels of the protein in the cells and thus inhibiting its ability to prevent tumor formation. The more sugar your body needs to break down, the higher the levels of this chemical, and the higher your risk of developing malignant tumors.

“Accumulation of methylglyoxal is found in cancer cells undergoing active metabolism,“ Mr. Kong said. ”People whose diet is poor may also experience higher than normal levels of methylglyoxal. The connection we unearthed may help to explain why diabetes, obesity, or poor diet can heighten cancer risk.”

MGO is challenging to measure on its own. Early detection of elevated levels is possible with a routine HbA1C blood test that measures your average blood sugar levels over the past two to three months and is typically used to diagnose diabetes. This new research may provide a mechanism for detecting early warning signs of developing cancer.

“In patients with prediabetes/diabetes, high methylglyoxal levels can usually be controlled with diet, exercise and/or medicines. We are aiming to propose the same for families with high risk of cancers, such as those with BRCA2 mutation,” Mr. Kong said.

More research is needed, but the study’s findings may open the door to new methods of mitigating cancer risk.

“It is important to take note that our work was carried out in cellular models, not in patients, so it would be premature to give specific advice to reduce risk on this basis. However, the new knowledge from our study could influence the directions of future research in this area, and eventually have implications for cancer prevention,” he said.

“For instance, poor diets rich in sugar or refined carbohydrates are known to cause blood glucose levels to spike. We are now looking at larger cancer cohorts to connect these dots.”

The Diet and Cancer Connection

Dr. Graham Simpson, medical director of Opt Health, stated in an email: “It’s genes loading the gun, but your lifestyle that pulls the trigger. Every bite of food you take is really information. It’s either going to turn on your longevity genes or it’s going to turn on your killer genes. So cancer is very much in large part self-induced by the individual diet.”

A 2018 study published by Cambridge University Press found an association between higher intakes of sugar-sweetened soft drinks and an increased risk of obesity-related cancers. Research published in the American Journal of Clinical Nutrition in 2020 concluded that sugars may be a risk factor for cancer, breast cancer in particular. Cancer cells are ravenous for sugar, consuming it at a rate 200 times that of normal cells.

Healthy Dietary Choices for Reducing Cancer Risk

A consensus on the best dietary approach for reducing cancer risk has yet to be determined, and further research is needed. However, the new findings of the Cell study on MGO support reducing sugar intake as a means to mitigate cancer risk. A study published in January in Diabetes & Metabolism shows that a Mediterranean diet style of eating may help reduce MGO levels.

In 2023, a study published in Cell determined that a ketogenic diet may be an effective nutritional intervention for cancer patients as it helped slow the growth of cancer cells in mice—while a review published in JAMA Oncology in 2022 found that the current evidence available supports a plant-enriched diet for reducing cancer risk.

Dr. Simpson stressed the importance of real food and healthy macronutrients with a low-carb intake for the health of our cells. “The mitochondria is the most important signaling molecule and energy-producing organelle that we have in our body. [Eat] lots of vegetables, healthy proteins, and healthy fats, fish, eggs, yogurt,” he said.

“Lots of green, above-ground vegetables, some fruits, everything that is naturally grown and is not processed.” For the Silo, Jennifer Sweenie.

Culture

Why Are Black Men At A Greater Risk For Prostate Cancer?

June 2, 2023 The Silo Leave a comment

As a Black man and a spiritual leader in the Linden community, I am concerned and am a personal victim about the disproportionate impact of prostate cancer on Black men. It is unacceptable that Black men are about twice as likely to get and die from prostate cancer than white men. While we still do not know definitively why this is the case, there are several factors that contribute to this reality.

Genetics may play a role. Studies have shown that prostate cancer in Black men has a different genetic profile, and it is a more aggressive form of the cancer. Additionally, Black men are underrepresented in clinical trials, which limits our ability to understand the disease’s impact and identify effective treatments. Lack of access to healthcare and inconsistent screening programs also contribute to the higher mortality rates among Black men.

But it’s not just genetics or lack of representation in clinical trials that cause this disparity. The cost of care, limited access to quality healthcare, and systemic racism create a barrier to care and early detection. Add to that the economic challenges faced by many Black men, such as the cost of cancer care and the inability to take time off work to recover from treatment, and it’s clear there is a multi-layered issue that must be addressed.

We cannot afford to remain silent on this issue. We must educate ourselves and our communities on prostate cancer risks and symptoms and the importance of timely screening. We must push for universal access to healthcare and encourage participation in clinical trials. And we must work to break down systemic barriers and create an equitable system of cancer care for all, regardless of race or ethnicity.

As a cancer patient myself, I understand how harrowing a prostate cancer diagnosis can be. However, it’s essential not to let the diagnosis define you and have faith that you can overcome any obstacle. Supporting each other and bringing awareness to life-saving prostate cancer screening is critical to reducing the disparities faced by Black men with prostate cancer. For the Silo, Imam Alfred

For Donations:

Imam Alfred Ministry for Unity

https://www.gofundme.com/f/imam-alfred-mohammed-emergency-medical-expenses

More about the author:

Imam Alfred Muhammed is working within the African American community on issues of leadership, peace, and interfaith outreach. Imam Alfred has inspired inner-city youth to self-actualization, promoted healthy family relationships, and improved economic development in the Linden community. He is now fighting stage 4A prostate cancer and has been forced to limit his engagements while spending more than $70,000 usd on alternative healthy treatments.

Before his conversion to Islam the Imam Alfred Muhammad was raised as a Christian in rural Virginia. His journey in religious leadership began in childhood as a Baptist preacher, but in 1960 the young minister Muhammad converted to the Nation of Islam. While in the NOI his desire was driven to become active in the 1960s Civil Rights Movement. Most notably, the Imam managed voter registration drives and worked closely with the lieutenants of Dr. Martin Luther King, Jr.

Sci-Tech

Using Laser Technology to Detect Cancer Cells

May 3, 2023 The Silo Leave a comment

We’ve come a long way since hearing Dr. Evil of Austin Powers’ movie fame describe “a sophisticated heat beam, which we call ‘a laser’ ” to take over the world, or sitting in awe watching Jedi knights in Star Wars blast through enemies using lightsabers.

Now in real life, lasers are being used to detect cancers cells.

Cancer tumors have the ability to break off of their primary site and spread from their primary organ to other sites of the body via the bloodstream and lymphatic system. The spreading of cancer, known as “metastasis”, is the leading cause of cancer-related death. Although, there are currently blood tests designed to detect cancer cells in the blood, known as circulating tumor cells, these test many times cannot pick up minimal cancer cells released early on. If these current tests return as positive, this frequently means that there is a high level of cancerous cells in the blood that have spread to other organs.

However, the diagnosis and treatment of these cancer cells in the blood may soon change.

In a recent study published in Science Translation Medicine, researchers have devised a laser that can detect these malignant cells and ‘zap’ them from outside of the body. The current standard methods of detection have limited sensitivity for picking up minimal cells at early stages of the disease, therefore possibly missing an opportunity to eliminate them at a treatable juncture. A team led by biomedical engineer Vladimir Zharov, director of nanomedicine at the University of Arkansas for Medical Sciences, has developed a method in hopes of changing that modality.

In studies with melanoma, they have coupled a laser with an ultrasound detector to create a ‘Cytophone,’ a device that identifies cells acoustically.

To break it down, a laser is first shined on the surface of a person’s skin, penetrating right into some of the near-surface blood vessels. The passing melanoma cells will then ‘heat up’ because of their darker pigment and create a small ‘acoustic wave’ that then gets picked up by the ultrasound detector. Melanoma cells absorb more of the energy from the laser because of their dark pigment, allowing them to heat up quickly and expand.

This devised method can pick up a single circulating tumor cell per liter of blood, which makes this up to approximately 1,000 times more sensitive than other available methods of detection that typically examine only about 7- 8 milliliters of a sample of blood. Additionally, the cytophone was able to detect small clots of blood that could potentially grow and lead to another set of harmful consequences.

They have tested this on 28 patients with melanoma and 19 healthy volunteers.

Researchers were able to discover that within as little as 10 seconds and as long as 1 hour, the cytophone was able to detect circulating tumor cells in 27 of the 28 patients. It also did not return any false positives on the healthy volunteers. Moreover, it was found that when the energy level of the laser was turned up (still to a safe intensity) that the amount of circulating tumor cells came down over the hour, without causing any side effects.

Although the mechanism will likely not destroy all of the patient’s cancer cells, it can help in several different ways. Initially, it can be used in high-risk individuals as a screening tool to detect cancer cells in the blood. Similar to mammograms in breast cancer, it can be added to skin checks in patients that are at high risk for melanoma. While undergoing treatment, it could potentially be used to monitor the effects of that particular treatment, in addition to or separate from imaging and other blood tests, to determine if the circulating cancer cells in the blood are decreasing. Following the completion of treatment, it can be used to monitor for relapse of disease.

Even though this has been tested recently in melanoma, and the dark pigment of melanin plays a role in its detection, Zharov and his colleagues are currently working to develop methods of ‘tagging’ other cancer cells with small nanoparticles to be able to ‘heat up’ and be distinguished from the normal cells. This study holds promise but it now needs to be expanded to in a larger population including patients with a higher content of melanin. For the Silo, Jerry McGlothlin.

Movies aside, the future holds promise in the new hope of using lasers to fight off the evil invasions of metastasis.

About Joshua Mansour, MD…

Dr. Joshua Mansour is a board-certified hematologist/oncologist working and in the field of hematopoietic stem cell transplantation and cellular immunotherapy in Stanford, California. In June 2019 he was a recipient of the ‘40 Under 40 in Cancer’ award. Abstracts, manuscripts, and commentaries by Dr. Mansour have been published in more than 100 esteemed journals and media outlets including Canada Free Press, Today’s Practitioner, Physician’s News, and KevinMD. He has given countless presentations at conferences and other institutions, and he has helped design and implement clinical studies to evaluate current treatment plans, collaborated on grant proposals and multi-institutional retrospective studies that have been published. Joshua Mansour. M.D. has been featured on Fox Television.

Sci-Tech

Why Radiation Protection Makes Sense- even at ‘Low’ Exposure levels

October 5, 2022 The Silo 1 Comment

Radiation is all around us.

It occurs naturally in our environment, coming to us from the sun, from the soil and foods that we eat, and in the air that we breathe. It is omnipresent across a diverse cross section of industries. We tend to associate radiation with the nuclear industry, but the reality is that we come across radiation sources in numerous other areas: construction, health care, oil and gas, research, manufacturing, food processing – to name just a few.

With radiation being everywhere in our lives, it is not surprising that it garners a lot of attention, curiosity and, often, worry.

With more than 15 years as a career radiation protection professional, I’ve had to respond to many occupational radiation safety questions — some have related to regulations and compliance, others to potential health effects of exposure and ways to minimize such exposure. In all cases, it is best to rely on well established radiation physics concepts and scientific data, where available.

While there is not much that we can do to escape natural background radiation exposure, we do want to avoid any unnecessary exposure to high levels of radiation, such as the potential hazard due to elevated radon (a radioactive gas) in our homes and workplaces.

Radon testing of homes is the simplest first step you can take to protect yourself and your family from radon gas, but all too often we do not make the time to educate ourselves and make this a priority. Workplaces are required to have a radiation protection program in place that is appropriate for the type of radiation and potential risk in their industry. But it takes time and investment to develop these programs, and it requires the commitment of both employers and workers to put these programs into practice.

Our challenge is that radiation and its associated risks are not always well understood.

On the one hand, we do not wish to alarm anyone unnecessarily, yet we want to make sure that the public, workers and employers are aware of the steps they need to take to stay safe. Remember, we are talking about an “invisible” hazard that very rarely causes ill health effects in the short-term. Additionally, the existing radiation protection models are built on what we call the linear no-threshold concept, which, in simple terms, is based on studies of the atomic bomb survivors from the Second World War in Japan and other high-exposure situations, and extrapolates the information to the potential health effects of low exposures.

An agency of the World Health Organization (WHO) recently published a study on the health effects of low-level exposure to radiation that provides data to support the validity of the linear no-threshold model. We encourage all who read the study (available at The Lancet Haematology) to not get alarmed and to keep the study conclusions in perspective.

It suggests that extended exposure to low level of radiation increases the risk of developing leukemia.

A frightening statement, but we have to keep in mind that the increased risk is small, in line with what we have estimated based on the modeling concepts. This boils down to two things: first, it is important that we continue to apply the ALARA principle — “As Low as Reasonably Achievable” — to all our of interactions with radiation; and second, that we continue to view the numbers associated with radiation and risk in the proper context. The study points to a “small increase” of risk of dying from cancer from low levels of radiation exposure.

Let’s put this into perspective.

If we extrapolate this study’s conclusions for nuclear workers to persons living near Canadian nuclear plants, people are 6,000 times more likely to die in a car accident, than to die from leukemia due to doses received from reactor plant emissions. Yet most of us think nothing of driving to work, driving our kids to school, or driving to visit friends and family. The radiation risk is there, but it is significantly smaller than the risks we accept every day, often without even thinking or worrying about them.

More research is required on the health risks from low-level radiation exposure, and there are efforts underway around the world to make it happen. At the Radiation Safety Institute, we will be looking forward to hearing about more study results. In the meantime we invite all people who are interested in the subject of radiation safety, who have a question or a concern, to reach out to our Free Information Service at 1-800-263-5803 or by e-mail at info@radiationsafety.ca. Let’s keep the conversation going. For the Silo, Laura Boksman Chief Scientist at the Radiation Institute of Canada.

Sci-Tech

Cellular Therapy In Mice Means Aging Reversal In Humans Possible

June 24, 2022 The Silo Leave a comment

Salk researchers treated mice with anti-aging regimen beginning in middle age and found no increase in cancer or other health problems later on

LA JOLLA—Age may be just a number, but it’s a number that often carries unwanted side effects, from brittle bones and weaker muscles to increased risks of cardiovascular disease and cancer. Now, scientists at the Salk Institute, in collaboration with Genentech, a member of the Roche group, have shown that they can safely and effectively reverse the aging process in middle-aged and elderly mice by partially resetting their cells to more youthful states.

“We are elated that we can use this approach across the life span to slow down aging in normal animals. The technique is both safe and effective in mice,” says co-corresponding author Juan Carlos Izpisua Belmonte, professor in Salk’s Gene Expression Laboratory and holder of the Roger Guillemin Chair.

“In addition to tackling age-related diseases, this approach may provide the biomedical community with a new tool to restore tissue and organismal health by improving cell function and resilience in different disease situations, such as neurodegenerative diseases.”

As organisms age, it is not just their outward appearances and health that change; every cell in their bodies carries a molecular clock that records the passage of time.

Cells isolated from older people or animals have different patterns of chemicals along their DNA—called epigenetic markers—compared to younger people or animals.

Scientists know that adding a mixture of four reprogramming molecules—Oct4, Sox2, Klf4 and cMyc, also known as “Yamanaka factors“—to cells can reset these epigenetic marks to their original patterns. This approach is how researchers can dial back adult cells, developmentally speaking, into stem cells.

In 2016, Izpisua Belmonte’s lab reported for the first time that they could use the Yamanaka factors to counter the signs of aging and increase life span in mice with a premature aging disease. More recently, the team found that, even in young mice, the Yamanaka factors can accelerate muscle regeneration. Following these initial observations, other scientists have used the same approach to improve the function of other tissues like the heart, brain and optic nerve, which is involved in vision.

In the new study, Izpisua Belmonte and his colleagues tested variations of the cellular rejuvenation approach in healthy animals as they aged. One group of mice received regular doses of the Yamanaka factors from the time they were 15 months old until 22 months, approximately equivalent to age 50 through 70 in humans. Another group was treated from 12 through 22 months, approximately age 35 to 70 in humans. And a third group was treated for just one month at age 25 months, similar to age 80 in humans.

“What we really wanted to establish was that using this approach for a longer time span is safe,” says Pradeep Reddy, a Salk staff scientist and co-first author of the new paper. “Indeed, we did not see any negative effects on the health, behavior or body weight of these animals.”

Compared to control animals, there were no blood cell alterations or neurological changes in the mice that had received the Yamanaka factors. Moreover, the team found no cancers in any of the groups of animals.

When the researchers looked at normal signs of aging in the animals that had undergone the treatment, they found that the mice, in many ways, resembled younger animals. In both the kidneys and skin, the epigenetics of treated animals more closely resembled epigenetic patterns seen in younger animals. When injured, the skin cells of treated animals had a greater ability to proliferate and were less likely to form permanent scars—older animals usually show less skin cell proliferation and more scarring. Moreover, metabolic molecules in the blood of treated animals did not show normal age-related changes.

This youthfulness was observed in the animals treated for seven or 10 months with the Yamanaka factors, but not the animals treated for just one month. What’s more, when the treated animals were analyzed midway through their treatment, the effects were not yet as evident. This suggests that the treatment is not simply pausing aging, but actively turning it backwards—although more research is needed to differentiate between the two.

The team is now planning future research to analyze how specific molecules and genes are changed by long-term treatment with the Yamanaka factors. They are also developing new ways of delivering the factors.”

At the end of the day, we want to bring resilience and function back to older cells so that they are more resistant to stress, injury and disease,” says Reddy. “This study shows that, at least in mice, there’s a path forward to achieving that.”

Belmonte is currently an Institute Director at Altos Labs, Inc., in addition to being a professor at the Salk Institute.Other authors included Mako Yamamoto, Isabel Guillen Guillen, Sanjeeb Sahu, Chao Wang, Yosu Luque, Javier Prieto, Lei Shi, Kensaku Shojima, Tomoaki Hishida and Concepcion Rodriguez Esteban of Salk; Kristen Browder, Zijuan Lai, Qingling Li, Feroza Choudhury, Weng Wong, Yuxin Liang, Dewakar Sangaraju, Wendy Sandoval, Michal Pawlak, Jason Vander Heiden and Heinrich Jasper of Genentech, Inc.; Amin Haghani and Steve Horvath of UCLA; Estrella Nuñez Delicado of Universidad Católica San Antonio de Murcia; and Pedro Guillen Garcia of Clínica CEMTRO.The study was supported by Universidad Católica San Antonio de Murcia (UCAM), and Fundación Dr. Pedro Guillén.

DOI: 10.1038/s43587-022-00183-2

About the Salk Institute for Biological Studies:
Every cure has a starting point. The Salk Institute embodies Jonas Salk’s mission to dare to make dreams into reality. Its internationally renowned and award-winning scientists explore the very foundations of life, seeking new understandings in neuroscience, genetics, immunology, plant biology and more. The Institute is an independent nonprofit organization and architectural landmark: small by choice, intimate by nature and fearless in the face of any challenge. Be it cancer or Alzheimer’s, aging or diabetes, Salk is where cures begin.

Shinya Yamanaka, MD, PhD, a senior investigator at the Gladstone Institutes — which is affiliated with UCSF — won the 2012 Nobel Prize in Physiology or Medicine for his discovery of how to transform ordinary adult skin cells into cells that, like embryonic stem cells, are capable of developing into any cell in the human body. Yamanaka shared the prize with John B. Gurdon of the Gurdon Institute in Cambridge, England.

Culture

Winners And Losers Around The World In School Lunches

February 3, 2020 The Silo Leave a comment

School has ‘been in’ for awhile now. Does your child’s school lunches sound healthy to you? How do you think it compares to school dinners from around the world? And how much do school meals affect energy levels for post-lunch learning and does that have an impact on PISA test results?

Check out this infographic to discover what the school meals of other countries look like and how each nation scores on the PISA test. For the Silo, Dinah Makani.

around the world in school lunchboxes infographic — CLICK ME to visit this graphic’s sponsor 🙂

Reviews

What We Learn From The Death Of A Spouse And How To Find Love Again

September 23, 2019 The Silo 2 Comments

He had no idea his life would change so significantly……For 31 years, Dennis and Hope Freed had a fulfilling marriage. They raised a family, built a home, and shared their dreams with one another and their two sons.

Then Hope got cancer, and their lives changed drastically overnight. She fought a long brave battle, and went through over 250 chemotherapy treatments, but on April 7, 2012, on an evening that heralded Passover in the United States and Easter in Israel, she died.

Dennis Freed’s beloved wife and best-trusted friend had gone, leaving him alone to figure out a future he’d never imagined. For the first year, he sorted through what society expected of a long-term caregiver and widower. Eventually, Dennis emerged from mourning, his heart ready for life’s next chapter. Is there love after marriage?

In Love, Loss and Awakening, Dennis Freed tells the story of how he began to go out with women again. He shares the reality of dating at age 50-plus—how he endured the awkward and hilarious encounters and embarrassments a man experiences when he hasn’t been on a date with a new woman for decades. Dennis’s book chronicles how one finds love after the death of a spouse. He describes his courageous and uplifting journey through sorrow, his search for new love, and his rediscovery of love and happiness.

Drawing upon the wisdom and personal experiences he acquired dating middle-aged women in all the wrong places, Freed takes the mystery out of the many lessons he learned. Dennis found out that as a widow or widower you can find love again, but it’s a difficult road. Love isn’t unique to the person you loved first. That love never fades, but your heart has room for more. You can get love back in your life. Your new love becomes a special love in its own right.

Here are just a few of the valuable insights:

Hole Heart/ Whole Heart

When you lose your best, most trusted friend, the hardships just begin. You are now alone. Your whole heart collapses to half its size. It transforms into a Hole Heart. The process of resurrecting it to wholeness is like Lego construction, built one little brick at a time. At first, bricks of varying shapes and sizes are sorted through and meticulously placed. Slowly they assume the weight and shape of your newly imagined Whole Heart.

Learn How to Be Physical, Affectionate, and Intimate

You spent thirty-plus years kissing no one but your spouse. If you spend your time worrying about the “what if” instead of enjoying the right now, it will rob you of your joy today. Sometimes you just have to learn something new, like all the kissing pleasures one never experienced. It’s not such a bad idea. Understand that it takes time and practice, and that each person you meet is unique. You’ll make hurtful intimacy mistakes just like a teenager. You’ll make stupid and inconsiderate mistakes. It’s a fact. Practice and learn so that when the right person comes along, you’ll be ready.

A Hundred Bottles of Beer on the Wall

You are going to date a lot of people. It is okay to be sad, mad, depressed, empty, lost after a date that isn’t perfect. Embrace the journey! Feel! Live it! Then get on to the next one so your failures don’t consume you. Have fun searching. Let your dating escapades become the target of jokes for your friends. Entertain them with style!

Love, Loss and Awakening

Dennis P. Freed

List $ 12.95US

88 pages, trade softcover, also available in ebook version

ISBN 978-0-9971916-1-5

Tolawaken Press

The death of a loved one is devastating, and can leave us questioning our new path. Will I ever want to find love again, and if so, how do I find it? What’s appropriate behavior for a widowed fifty-four-year-old? Should I explore dating sites? Meet women in bars? Rely on introductions from friends? The questions far outnumber the answers. In Love, Loss and Awakening, Dennis Freed shares his experiences and his journey to new love and the rediscovery of happiness.

For more information, visit www.LoveLossandAwakening.com

About the Author

Dennis P. Freed is a native of Brooklyn, New York, and, from age three, grew up in Oceanside, Long Island, where he later raised his family. He earned a BS in Civil Engineering at the University of Rhode Island. After a stint as a structural engineer, he entered the Construction Management and Development profession in New York City, where he has led teams to construct and develop more than sixty-five buildings. Also an associate professor at Pratt University in New York, he teaches Construction Management to architecture students.

What People Are Saying

“Love, Loss, and Awakening is an engaging story of how one man bounces back after losing the love of his life. It is an ode to the power of being in relationship, especially when faced with incredibly difficult and heartbreaking loss. And it is with much humor that Dennis Freed takes the reader on a journey to find what we are all looking for to be joyous and fulfilled in relationship.”

—Harville Hendrix, Ph.D., and Helen LaKelly Hunt, Ph.D., Creators of Imago Therapy and authors of Getting the Love You Want

“This is a story of digging deep after loss, finding that being with another is worth the risk, and staying open to lessons both human and Divine. At times an excruciating memoir of living with cancer, at others, a combination of ‘How To’ and, more useful, ‘How NOT To’ of middle-aged dating. Those who have loved deeply will be reminded of what they have or have lost; for others, it’s the promise of how good a relationship can be. The book has a happy ending, yet acknowledges that seeking love must always include a willingness to lose again.”

—Cynthia Wall, LCSW, author of The Courage to Trust: A Guide to Building Deep and Lasting Relationships

“Get ready to cry, laugh, cringe, and howl with wonder and delight as you go through Dennis Freed’s amazing experiences after the loss of his wife. He offers heartfelt real-life insights on how to cope with the despair and overcome the pain so you can face the world and find love and happiness anew.”

—Paul J. Krupin, author of Words People Love to Hear Simple Verbal Recipes for Making the People Around You Feel Good

Earth

Record Number Of Clean Beach Blue Flags Now Flying

June 21, 2019 The Silo 1 Comment

More Canadian beaches and
marinas awarded Blue Flags

2018 is another record year for Canada’s waterfronts, 27 beaches and nine marinas have been awarded a coveted Blue Flag, including our very first coastal flag at beautiful Aboiteau Beach, NB. The Blue Flag is the internationally recognized symbol of environmental excellence for beaches and marinas. Read on to find the best waterside spots to spend your Victoria Day weekend.

Time for
the Government
to step up on
plastic waste

Only 11 per cent of Canada’s plastic waste is recycled. Let that sink in for a minute. This problem goes way beyond individual changes, we need the Federal Government to step up and take meaningful action before it’s too late. Sign the petition now to ask for a plastic free environment.

Banned chemicals found in products that babies chew, play and nap on

A new study reveals that 86 per cent of tested products sold in Canada contain toxic chemicals, some of which are banned. Baby bibs, blankets and more were found to contain water and stain resistant chemicals linked to hormone disruption, and even cancer. Find out how you can take action.

Tell Canada that all high-carbon projects need an impact assessment

What the frack?! The Canadian government is proposing to exempt fracking and in situ tar sands from the new federal environmental review process. We have until June 1st to fix this – send a letter now to tell the government that ALL high-carbon projects should get an impact assessment.

Culture

Identify Toxic Cosmetics

January 30, 2019 The Silo Leave a comment

What does the ingredients list above represent? It’s taken from the label of a popular name brand soap advertised with fresh faces, and as leaving no residue on the skin. Would it surprise you? Perhaps you recognized it, but thought well it’s being sold in stores so it must be safe.

The good news is that since 2006, Canadians have been provided with mandatory labeling on personal care products. Health Canada has even gone a step further providing a “hotlist” or list of prohibited or restricted chemicals . This is a huge step above our neighbours to the south, whom currently have minimal regulation on personal care products. Canada is on the right track, but is still a few steps behind the European Union, where personal care products are held to stringent guidelines.

The bad news is that even though there are guidelines set of by Health Canada, some of the products on the market today still contain chemicals, with similar structures to those chemicals that have been restricted. And if something shares a similar structure it is likely to interact with the human body in a similar fashion, thus causing similar health concerns.

What at can you do? The good folks at the David Suzuki Foundation performed a Survey of Canadians and their use of personal care products, and from this developed a “dirty dozen” of chemicals to avoid. Results of their survey demonstrated that 80% of products contained at least one ingredient on the list, and only 20% did not contain any. By visiting the www.davidsuzuki.org and searching “What’s Inside? That Counts,” you can download your own copy of the list, or even visit the mobile site when you are out shopping.

Why does this all matter? Many of the chemicals that are found in personal care products can bio-accumulate, meaning they can increase in concentration over time, and be passed on to our next generations. There is also well documented evidence of effects within the human body caused chemicals affecting the endocrine system. Within the human body endocrine disruptors have been implicated in neurological diseases, reproductive disorders, thyroid dysfunction, immune and metabolic disorders. Cancer is also another health concern that has been linked to many of the chemicals found in personal care products.

What about my health? As a naturopathic doctor I am always thinking from a preventative medicine point of view. The more I learn, I continue to look for natural/chemical free personal care products. Also important is optimizing your body’s innate ability to remove build up of chemicals through organs such as liver, skin, and kidneys. As always, prevention is the best medicine, and becoming a savvy consumer involves reading labels and asking questions. For the Silo, Ashley Beeton Bsc. ND.

Earth

Canada Reassessing Glyphosate Roundup Herbicide Link To Cancer

January 25, 2019 The Silo Leave a comment

It’s been nearly four years since we published the article below and the water surrounding glyphosate use in Canada is still murky. Roundup is currently being used in an official capacity in certain situations by government agencies such as the Ministry of the Environment to fight the invasive species Phragmites. Let’s review the earlier article:

Dear friends across Canada, top scientists warn the most commonly used herbicide in the world probably causes cancer. Monsanto is demanding the World Health Organization retract their ground-breaking report. And experts say the only way to ensure the science is not silenced is if the public demands action, now. The regulatory system is renowned for being secretive and captured by the agro-chemical industry. But we have a unique moment right now — Canada is officially reassessing glyphosate, with similar processes underway in the US, Europe, and Brazil. And the Netherlands, Sri Lanka, and El Salvador are all looking at a ban. [However, it must be noted that as of today’s posting, Canada Health’s Food Safety Inspection statement is that glyphosate formulations ARE safe http://www.hc-sc.gc.ca/fn-an/gmf-agm/seralini-eng.php CP]The threat is clear — this poison is used on our food, our fields, our playgrounds, and our streets. Let’s get it suspended.

Join the urgent call and tell everyone: https://secure.avaaz.org/en/monsanto_dont_silence_science_loc_cn/?bsOTIab&v=57275

Monsanto is up in arms. Glyphosate brings in $6 billion per year. It is the basis of RoundUp, the chemical cornerstone of Monsanto’s Genetically Modified empire. The company says the WHO report ignored studies showing glyphosate is safe. But these scientists are 17 of the world’s top oncology experts, not a bunch of crazies. They comprehensively reviewed independent studies, excluding those done by companies seeking product approval. Regulators rely mainly on tests done by the companies trying to sell the poisons!

Key results are kept from the public because they contain ‘commercially confidential information’, and 58% of the scientific panels in the EU Food and Safety Agency are linked to the sector. It’s nuts, but that is the system we have. And that’s why it’s going to take all of us to make sure this crucial independent report isn’t ignored. Some countries have already put bans on glyphosate. Now with the EU, the US, Canada, and Brazil all reviewing it, we have an incredible chance to turn the tide worldwide.

Fifty years ago Monsanto’s pesticide DDT was everywhere until the seminal book Silent Spring showed it could cause cancer — a decade later it was banned. If this could cause cancer, let’s not let it be sold for ten more years. Let’s demand emergency precautionary action now.

Join now and spread the word: https://secure.avaaz.org/en/monsanto_dont_silence_science_loc_cn/?bsOTIab&v=57275

We’ve done it before — helped win a moratorium on bee-killing neonicotinoids in the EU and stop a Monsanto mega seed factory in Argentina. Now let’s protect our health and make sure we aren’t being used as lab rats. This could be a breakthrough moment in the fight for the safe, sustainable agriculture our world needs. With hope, Bert, Marigona, Antonia, Oliver, Alice, Emily, Danny, Nataliya, Ricken and the whole Avaaz team.

More information: New study points to link between weedkiller glyphosate and cancer (FT) http://www.ft.com/cms/s/0/8b79a572-cf14-11e4-893d-00144feab7de.html#axzz3XOmCcv9c

Supplemental-

Monsanto seeks retraction for report linking herbicide to cancer (Reuters) http://in.reuters.com/article/2015/03/24/monsanto-herbicide-idINL2N0WP0UM20150324

Weed Killer, Long Cleared, is Doubted (New York Times) http://www.nytimes.com/2015/03/28/business/energy-environment/decades-after-monsantos-roundup-gets-an-all-clear-a-cancer-agency-raises-concerns.html

The Real Reason to Worry About GMOs (Mother Jones) http://www.motherjones.com/tom-philpott/2015/03/bittman-right-its-not-gmos-its-how-theyre-used

Groups seek EPA glyphosate review after WHO ‘carcinogenic’ link (Agri Pulse) http://www.agri-pulse.com/Groups-seek-EPA-glyphosate-review-after-WHO-carcinogenic-link-03272015.asp

More sources: https://avaazmedia.s3.amazonaws.com/Roundupsources.pdf

Culture

Glyphosate From Roundup Pesticides Does Not Belong In Canadian Food

September 18, 2018 The Silo Leave a comment

Let’s cut right to the chase: Do you know what’s in your lunch? We were curious, so we decided to investigate further.

We tested popular foods such as Cheerios, a Tim Hortons bagel, Ritz crackers and Fontaine Santé hummus and the results were overwhelming: 80 per cent of the foods tested contained the harmful chemical glyphosate. Glyphosate, Canada’s top-selling weed killer and key ingredient in Monsanto’s product Roundup, is of particular concern because of its links to cancer.

The unchecked use of glyphosate and widespread contamination of the foods that you and your children eat every day is not acceptable.

Just last month, a California court ruled that Monsanto’s glyphosate–based pesticide, contributed to an American citizen’s cancer. The court case revealed documents showing Monsanto manipulated scientific research and downplayed the risk of its products for decades. This case is just one of several thousand lawsuits against Monsanto (now owned by Bayer).

In Canada, the Pest Management Regulatory Agency (a department of Health Canada) recently reauthorized glyphosate for another 15 years. We are calling on the federal government to bring our outdated toxics and pesticide laws into the 21st century and remove harmful chemicals like glyphosate from our food. With your help, we can make this happen. For more information check out this report at whatsinyourlunch.ca For the Silo, Muhannad Malas.

Supplemental- Jurors give $289 Million USD to man they say got cancer from Roundup weed killer.

Earth

Almost 200,000 Canadian homes have Dangerous levels of Radon

November 24, 2015 The Silo Leave a comment

November is Lung Month and also Radon Action Month, and health officials are urging Canadians to test their homes for radon.

It is estimated that 3,000 Canadians die each year from lung cancer caused by exposure to radon. Yet only about 4% of Canadian homes have been tested for radon, the second leading cause of lung cancer after smoking. As a result, most Canadians are unaware of the deadly gas that may be present in their homes.

What is radon?
Radon is a naturally forming, radioactive, colorless, odorless and tasteless gas. It is found in almost all soil, and is produced by a natural process as uranium breaks down into radium and then into radon gas. Radon in turn breaks down into solid radioactive elements known as “radon progeny” (such as polonium – 218) that attach to airborne particles. Radon enters a home through cracks in the floor or walls of the basement or foundation.

Radon and your health
Because they are radioactive, radon and radon progeny emit alpha particles, a high-energy radiation that damages DNA in human cells and causes lung cancer. When radon is inhaled, particles become lodged in the lungs where they continue to emit alpha particles. Some studies have also suggested a link between radon and leukemia, though it can’t be definitely determined and more research is needed.

What you can do
Here are a few simple steps you can take to control radon levels in your home and help protect those you love:

1) Test for Radon. The first step in managing the risk of radon is to have your home tested. Every home is unique, and a home with dangerous radon levels can be next door to a home with virtually no radon. Any radon level higher than 200 becquerels per cubic metre (200 Bq/m³) is considered by health authorities to be unsafe. Testing should always be conducted by a qualified contractor, and should include both short-term and long-term testing. Look for a radon mitigation professional who is C-NRPP certified online.

2) Mitigate Radon. A qualified radon mitigation contractor will help you determine the most effective way to reduce radon in your home. These techniques include:

a) Sealing cracks. Since radon enters your home through cracks in the floor and the foundation, sealing cracks and leaks is an important first step. However, sealing cracks will limit but not completely stop the flow of radon into a home.

b) Suction. On effective method of eliminating radon includes inserted pipes into or below the foundation slab. These pipes are then connected to a vent fan that pulls radon from below the house and releases it out into the open air.

c) Depressurization. This generally involves drilling a hole in the basement floor and extending a pipe beneath the slab of the house. The pipe runs up through the home and then vents outward with the help of an inline fan.

d) Ventilation. Installing a heat recovery ventilator increases ventilation by drawing outside air into the house and expelling radon-contaminated air. Air is warmed or cooled as needed, and air filtration can be added to filter the outdoor air coming in.

e) Filtration. While filtration is not the only method by which radon can be reduced, research has shown that even standard HEPA filters can reduce radon by as much as 85%. And while air cleaning is not recommended to control radon because most filtration systems, even HEPA filters, are incapable of stopping the tiniest particles to which radon progeny adhere. IQAir’s HyperHEPA filtration, on the other hand, filters particles down to 0.003 microns – the smallest particles that exist.

Given that November is Lung Month and Radon Action Month in Canada, now is as good a time as any to test your home for radon. The sooner you have your home tested, the sooner you will be on your way to ensuring yours is a healthy home for you and your family.

This article is brought to you by our friends at IQAir North America, Inc., a member of the Swiss-based IQAir Group that develops, manufactures and markets innovative air purifiers and air quality products for indoor environments around the globe. IQAir is the exclusive educational partner of the American Lung Association for the air purifier industry. Jarrod Barker

UPDATE- From Futurism: “Say goodbye to ‘cracks’, self-healing concrete has arrived.” Concrete that is mixed with Bacteria to self-heal and last for two hundred years. https://www.facebook.com/futurism.co/videos/496701823842355/

Culture

Recover From A Hyper Summer By Using Theanine

July 30, 2014 The Silo Leave a comment

While barbecues, sports leagues, family vacations, days at the beach and nights out with friends are fun, keeping up with summer recreation while maintaining a steady work schedule can be challenging, says Budge Collinson.

And before we know it, we’ll be back into the busy fall grind, getting kids up and off to school, participating in clubs and civic groups that have been on summer hiatus, and yes, before we know it, planning for holidays!

“We like to tell ourselves that there will be a period of rest before the next big thing, but usually there isn’t,” says Collinson, a food science expert with a passion for health and fitness. “The truth is, most of us like having full and often fast-paced lives, even if we tend to get worn out more quickly as we get older.”

Don’t resort to caffeine and other stimulants for a temporary energy boost, Collinson says.

“Replacing the nutrients that are depleted when you’re active is a much smarter way to maintain or increase your energy level, and many of those nutrients have long-term benefits as well,” says Collinson, who formulated an effervescent, natural multivitamin beverage called Youth Infusion, to make it easier to get all the essential nutrients and minerals in one 6-ounce drink.

He discusses the revitalizing powers of specific nutrients:

CoQ10 for that extra energy boost. Every cell in your body uses CoQ10 to produce energy, but your heart needs it the most. CoQ10 can help balance your blood pressure, and its mature aging.

Arginine to help with your endurance during workouts and your daily routine. Arginine helps the cardiovascular system by assisting in nitric oxide production, making the arteries more elastic. It also supports the functioning of your hormones and s waste and promotes wound healing.

Theanine helps support better moods. Theanine is a calming extract of green tea. Clinical research indicates that it helps focus a distracted mind. To a lesser extent, theanine has also been shown to reduce anxiety.

Resveratrol: a versatile antioxidant for term peace of mind. Resveratrol promotes healthy circulation, prevents cholesterol oxidation and protects your entire cardiovascular system from the effects of dangerous free radicals. Initial research shows resveratrol helps defend the body against a number of diseases, including Alzheimer’s, heart disease, cancer and diabetes.
Vitamin D – for when the sun isn’t as bright as Up to 90 percent of the vitamin D the body needs comes from sunlight, which is in much shorter supply after summer. Vitamin D is required for the regulation of the calcium and phosphorus in the body. It also plays an important role in maintaining proper bone structure and supporting immunity.

About Budge Collinson

Budge Collinson was the beneficiary of his mother’s natural health formula as a sick baby, which led to a deep interest in health and wellness at a young age. After years of research and seeing the growing demand for natural products with clinical support, he founded Infusion Sciences,
www.infusionsciences.com. Collinson earned a bachelor’s degree in food and resource economics from the University of Florida and certification from the National Academy of Sports Medicine. Recently, he became a member of the American Academy of Anti-Aging Medicine and consistently attends the Natural Products Expo, where he learns the latest science and news about nutritious ingredients. Collinson is also a go-to source for media outlets across the country for healthy lifestyle and food source discussions.

Sci-Tech

St. Catharines New Highest Technology Hospital Is Impressive

August 30, 2013 The Silo 3 Comments

The Project: The 980,000 sq. ft. acute care community hospital replaces two aging facilities in the Niagara region and accommodates 375 acute care beds, with associated outpatient and support services.

Niagara Health System New Health Care Complex – St. Catharines Site "2oth Century NOT included" CP — New Health Care Complex – St. Catharines Site “2oth Century NOT included”

It provides a comprehensive range of clinical services including:

• a cancer centre serving 1,200 patients close to home, relieving them from the stress of travelling to Hamilton or Toronto for treatments

• a longer-term mental health service that includes 53 beds

• dialysis services

• cardiac catheterization services, which provides diagnostic investigation, reduces hospitalizations for heart disease and provides faster local care for residents of the Niagara region

The goal of this project was to provide Niagara Health System with a modern, state-of-the-art, one million square foot building capable of providing one million square feet of care.

In addition to design and construction management, PCL’s [ PCL comprises a family of general contracting companies and is the largest such organization in Canada and the fifth largest in the U.S. CP ]scope of work also included the procurement and installation of more than 25,000 pieces of medical equipment, as well as medical gas, head walls, nurse call system, information technology, audio visual, and security technology.

Some of the many interesting features that set this building apart include construction of the first radiation suites in the Niagara region, an enclosed ambulance bay to provide protection to incoming patients, an interior design that strategically locates departments to minimize clinical travel time by staff, and an exterior design that implements materials indigenous to the Niagara region.

Architectural

• Main Street feature wall using a combination of indigenous and complementary stones that tell a story of the geological formation of the Niagara Escarpment.

• Use of structural elements in the form of a tree at the main entry and cafeteria to create the canopy.

• First operating rooms in Canada to use Corian wall finishes.

• Integrated interior finishes and way finding system,using landmarks to help visitors and patients locate themselves in the facility.

• Enhanced use of natural light to infiltrate deeper into the building, with particular attention to patient spaces.

• An acoustical design at the building envelope to mitigate and isolate noise generated by a nearby train corridor.

Structural

• Blending structural elements with architectural finish and spectacle.

• Strategy of a structural grid system to maximize open spaces and floor to ceiling height.

• Foundation system and MRI inertia slab to address vibrations created by train traffic and a nearby machine stamping plant.

• Post Disaster design to address potential seismic event, to allow the facility to operate during and after as a relief centre.

• Use of cast-in-place elements to allow equipment flexibility.

Mechanical/Electrical

• Pandemic containment capability to deal with infectious outbreaks and disasters, allowing the facility to isolate building sections and departments.

• Building automation system, fully integrated with building elements and equipment to monitor and ensure optimal building performance.

• Back-up and dual power systems to ensure fundamental building and medical systems remain available and functioning at all times, including integration with the building automation system, to allow targeted load distribution to non fundamental systems to become available as required.

The Operating Theater. It's understandable if you think that this is a set from Star Trek- — The Operating Theater. It’s understandable if you think that this is a set from Star Trek-

Sustainability

• The project is targeted for LEED® certification. As part of the construction and design strategy, the project team developed several innovations and elements for a significant improvement of the target to LEED® Silver certification – from 26 to 35 points.

• Incorporated an energy efficient lighting strategy using natural lighting as much as possible, as well as the broad use of occupancy sensors and low energy lighting systems.

• Integrated and efficient cooling and heating systems, and an optimized building envelope system that helps to reduce greenhouse gas emissions.

• The overall energy strategy resulted in the Energy Model that realizes an energy savings of 46% relative to the Model Energy Code for Buildings, which is expected to produce savings to the client in excess of $1 million annually.

• Use of native and hardy plant species and an integrated storm water management program, including irrigation and water features to eliminate city water use for landscape elements.

A look at the state-of-the-art radiation treatment facility.

Supplemental- Corian mineral composite wall panels– http://www.architonic.com/pmpro/corian-panels-mineral-composite-panels-mineral-composite-materials-finishes/3240623/2/2/1

1000 Canadian projects now LEED Certified/What is LEED– http://www.dcnonl.com/article/id55463

B+H Architects, designers of St. Catherines new hospital- http://www.bharchitects.com/en/projects/129

PCL Construction, builders of St. Catherines new hospital– http://www.pcl.com/Pages/default.aspx

Earth

Fight Stress With Shinrin Yoku Forest Bathing

July 27, 2013 The Silo 1 Comment

Stress is ever present in current society, both personal stress and workplace stress contribute to the well documented link, between stress and chronic conditions. The most recent data available from Statistic Canada’s – National Population Health Survey, demonstrates that personal stress is predictive of the development of a chronic health condition over the next four years (Statistics Canada, 2003). The long term impact of these chronic health conditions can result in significant activity limitation from heart attack, diabetes, migraine, or arthritis or back problems. Even more daunting is the higher predictive value of death for individuals suffering from cancer, bronchitis/emphysema, heart disease or diabetes.

The practice of forest bathing itself is not a new concept. Prior to the industrial revolution being “in nature” was part of everyday life. The Japanese term Shinrin-yoku meaning “taking in the forest atmosphere or forest bathing” was officially coined by the Japanese Ministry of Agriculture, Forestry, and Fisheries in 1982. (Park et al. 2010)

This novel practice of being in nature, demonstrates a wide variety of health benefits from which individuals in modern society can stand to gain. With the increasing amount of individuals living in urban settings the exposure to nature is diminishing.

Field studies performed in Japan measured salivary cortisol levels (more commonly known as “stress hormone”) in university individuals. The students were divided into two groups, one to spend a day in a forest setting, the other in a city setting. Lower levels of stress hormone, as well as lower blood pressure and pulse rate was found in individuals in forest location. (Park et al. 2010)

Further evidence has been documented to the demonstrate the reduction of stress resulting from forest bathing, through the improvement immune function with exposure to the natural environment. Given that immune function is key in the prevention of chronic diseases this evidence is exciting. Natural killer cells as they are ingeniously named are cells within the immune system which kill tumours or virus infected cells, through the release of enzymes which break down the cells. In research studies natural killer cells have been found to be elevated for seven days after the forest bathing trip (Qing, 2010). This seven day window of improved immune function is great news for the weekend warrior in all of us.

Many of us who live in Brant-Halidmand-Norfolk are blessed with exposure to forest just outside our doorsteps. This being said it doesn’t mean we always take advantage of it, between commuting to work, family and social commitments, going from the house to the car may be the norm. For the Silo, Ashley Beeton.

References

Park, B.J., Tsunetsugu, Y., Kasetani, T., Kagawa, T., & Miyazaki, Y. (2010) The physiological effects of Shinrin-yoku (taking in the forest atmosphere or forest bathing): evidence from field experiments in 24 forests across Japan. Environ Health Prev Med, 15,18–26.

Statistics Canada. (2003) Stress and Well-being (No 82-003). Retrieved from http://www5.statcan.gc.ca/access_acces/alternative_alternatif.action?l=eng&loc=http://www.statcan.gc.ca/pub/82-003-x/2000003/article/5626-eng.pdf&t=Stress%20and%20well-being

Qing, Li. (2010) Effect of forest bathing trips on human immune function. Environ Health Prev Med, 15,9–17.

Preventing, Minimizing and Repairing Damage from Exposure

“The snow reflects the glare of the sun – and the damaging UV rays,” he says. “People who like skiing and snowboarding in the mountains are getting 4 to 5 percent more UV damage for every 1,000 feet they ascend above sea level.”

No matter how comfortable or cool the temperature feels, don’t be fooled.

TORONTO – Following restrictive sun exposure advice in countries with low solar intensity like Canada might in fact be harmful to your health, says the co-author of a new study on sunlight and vitamin D.

“Humans have adapted to sun exposure over many thousands of years and derive numerous physiological benefits from UV exposure, in addition to vitamin D,” said Baggerly, executive director of Grassroots Health and breast cancer survivor.

In Canada, vitamin D from sunlight can only be synthesized in the skin during the spring, summer and fall months, around midday, from 10 a.m. – 2 p.m., when the UV index is above three and your shadow is shorter than your height.

Vitamin D deficiency is an indication of sunlight deficiency.

About the Vitamin D Society:

MGO, a glucose metabolite, can temporarily destroy the BRCA2 protein, reducing its levels in cells and inhibiting its tumor-preventing ability.

Methylglyoxal–A Temporary Off Switch

The Methylglyoxal and Cancer Relationship

More research is needed, but the study’s findings may open the door to new methods of mitigating cancer risk.

The Diet and Cancer Connection

Healthy Dietary Choices for Reducing Cancer Risk

More about the author:

Now in real life, lasers are being used to detect cancers cells.

However, the diagnosis and treatment of these cancer cells in the blood may soon change.

In studies with melanoma, they have coupled a laser with an ultrasound detector to create a ‘Cytophone,’ a device that identifies cells acoustically.

They have tested this on 28 patients with melanoma and 19 healthy volunteers.

While there is not much that we can do to escape natural background radiation exposure, we do want to avoid any unnecessary exposure to high levels of radiation, such as the potential hazard due to elevated radon (a radioactive gas) in our homes and workplaces.

It suggests that extended exposure to low level of radiation increases the risk of developing leukemia.

Let’s put this into perspective.

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